Bioinformatics Centre
      (a Sub-DIC established at MGIMS in 1999 with funding from DBT, Ministry of Science & Technology, Govt of India)
   Biochemistry | JB Tropical Disease Research Centre | Mahatma Gandhi Institute of Medical Sciences, Sevagram

DATABASES & SOFTWARE

The following are the Databases and Software for retrieval of information, comparison and development of evidence based medicine for diagnosis, management & research.

1. MTB - PCDB: The Mycobacterium tuberculosis Proteome Comparison Database

  • MTB-PCDB is an online database with an integrated access to proteome sequence comparison data on five strains of Mycobacterium tuberculosis (H37Rv, H37Ra, CDC 1551, F11 and KZN 1435) sequenced completely so far

  • Currently hosts 40252 protein sequence comparison data

  • Proteome comparison data may be beneficial in discovery & development of TB drugs, vaccines and biomarkers

2. MycoProtease-DB a database of M.tb and NTM proteases

  • Contains protease information of Mycobacterium tuberculosis (MTB) complex and Nontuberculous Mycobacteria (NTM) at gene, protein and structural level whose complete genome sequence is available

  • Currently hosts 1324 proteases, which include 906 proteases from MTB complex with 237 distinct proteases & 418 from NTM with 404 distinct proteases

   

3. HPV-PDB (Human papillomavirus Proteome Database)

  • The Human papilloma Virus Proteome Database (HPV-PDB) developed at this centre, domiciles proteomic and genomic information on 150 HPV strains sequenced so far.

  • Easy expandability & retrieval of the strain specific data at one place, facility for sequence analysis & exploration potential of predicted structures, easy access to curate and annotate data through various search options etc are few of its important features.

  • Data may be helpful in exploring for designing the drugs and vaccines against several such strains of HPV

4. FilaDB: Filariasis patient information based database for better diagnosis, clinico-immuno monitoring and management

5 . TBDB: Tuberculosis patient information based database for better diagnosis, clinico-immuno monitoring and management.

6 . GynSoft: Gynaecology patient information based database for Indoor & Outdoor Patients records for better diagnosis, management.

7 . ObSoft: Obstetrics patient information based database for Indoor & Outdoor Patients records for better diagnosis and management.

8 . PsySoft: Psychiatry patient information based database for Indoor & Outdoor Patients records for better diagnosis and management.

9. ResPub: Database on JBTDRC Research publications (ResPub): Database on JBTDRC research publication in thrust areas, namely filaria and tuberculosis (1970-2013).