New drug attacks cancer-causing genes
Two recent papers attack two cancer-related problems using the same drug. They hope that it might improve survival in breast and lung cancer and halt obesity-related cancers. Researchers from Michigan State University in East Lansing are using novel molecular routes to attack cancer. The scientists were particularly interested in bromodomain inhibitors (BET inhibitors). BET inhibitors prevent the expression of certain growth-promoting genes and therefore slow tumor growth. The researchers have published two papers in the journal Cancer Prevention.
www.medicalnewstoday.com, March 31, 2018
Long-term antibiotic use may shorten women's lives
Taking antibiotics for a long time during late adulthood may be linked with a higher risk of death among women, according to the latest evidence. Antibiotics have been commonly prescribed by doctors for 70 years. These drugs have significantly reduced global rates of illness and death from infectious diseases. However, their widespread use has allowed some infectious organisms to adapt and become resistant to antibiotics. There are some side effects associated with antibiotics — including feeling sick, diarrhea, and fungal infections of the mouth, digestive tract, or vagina..
www.medicalnewstoday.com, March 26, 2018
Could Vitamin C Help Fight Tuberculosis?
A new study suggests that a low-cost nutrient could help drugs fight tuberculosis more effectively. The study found that anti-tuberculosis drugs killed more bacteria in laboratory mice when the mice received vitamin C. The authors say the findings could offer a low-cost, safe way to reduce the long treatment time for one of the world's deadliest diseases. They also say the vitamin supplement could offer a way to fight tuberculosis that is resistant to antibiotic drugs.
learningenglish.voanews.com, January 18, 2018
Gene therapy may boost stroke recovery
The study, carried out on mice, shows that turning on a gene inside cells called astrocytes results in a smaller scar and -- potentially -- a more effective recovery from injury. Researchers have found that a genetic trigger may improve the brain's ability to heal from a range of debilitating conditions, from strokes to concussions and spinal cord injuries. The study, carried out on mice, shows that turning on a gene inside cells called astrocytes results in a smaller scar and -- potentially -- a more effective recovery from injury.
zeenews.india.com, March 28, 2018
Scientists discover new human antibody that can prevent malaria infections
A team of scientists discovered a new human antibody that can prevent malaria infections by binding a specific portion of a surface protein found in almost all strains of the malaria parasite worldwide. Marie Pancera, Biologist at the Fred Hutchinson Cancer Research Center in Washington said that the research shows that the antibody called CIS43 protects against malaria better than any antibody that has been described before. The study was published in the journal Nature Medicine.
zeenews.india.com, March 20, 2018
New test may prevent antibiotic resistances from spreading
Scientists have developed a new “rapid test” that produces a cheaper and faster diagnosis on infectious diseases in just three hours thus preventing antibiotic resistances from spreading. The new method provides much faster diagnosis with the help of tiny electrodes that are fixed on the surface of a stamp-sized chip..
indianexpress.com,March 14, 2018
Obesity linked to increased DNA damage in breast epithelium of BRCA mutation carriers
Being obese or having a higher body mass index (BMI) while carrying a BRCA (BReast CAncer gene) mutation is positively linked with higher levels of damage to the DNA in normal breast gland cells, new research suggests. The results of the study will be presented Sunday, March 18, at ENDO 2018, the 100th annual meeting of the Endocrine Society in Chicago, Ill.
www.news-medical.net, March 19, 2018
Beneficial skin bacteria protect against skin cancer
Science continues to peel away layers of the skin microbiome to reveal its protective properties. In a study published in Science Advances on February 28, University of California San Diego School of Medicine researchers report a potential new role for some bacteria on the skin: protecting against cancer.
www.sciencedaily.com, March 01, 2018
Prescription NSAID pain relievers increase risk of irregular heartbeat, study shows
Some prescription pain relievers commonly used for arthritis and other conditions may come with a concerning heart risk. A study that looks at prescription non-steroidal anti-inflammatory pain relievers, or NSAIDs — like prescription-strength ibuprofen and naproxen — found that people taking them had an 18 percent higher risk of irregular heartbeat, also known as a trial fibrillation or a-fib. "It's important information for people, because these are commonly used drugs," said CBS News medical contributor Dr. Tara Narula, who is a cardiologist at Northwell Health.
www.cbsnews.com, March 21, 2018